But the men's champion, Paul Tergat will be defending his title for the fourth time in the Mexican eastern resort town of Veracruz.
"Loroupe has ran so many meetings. She's completely exhausted. It will be no good for her to run," Kenya Amateur Athletic Association (KAAA) spokesman Francis Nyatome said.
Loroupe, the three-time world half-marathon champion and world record holder, failed in her bid for an unprecedented double at the Sydney Olympic Games in September, but made a return to the course at the Great North Run half-marathon in England 10 days ago, where she finished runner-up to Paula Radcliffe.
Her absence will leave a depleted three-member Kenya women's team of Susan Chepkemei, Pamela Chepchumba and Milka Chepkieng to challenge champions South Africa for the team title.
The men's team also include Joseph Kimani, Patrick Ivuti, John Wako and Philip Rugut.