The Best Detox Cleanse Products of 2022: Everything From Daily Support to 30-Day Programs

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If you're feeling sluggish, run-down, or dealing with frequent colds, it may be a sign that your body could use a boost from the best detox cleanse. We’re exposed to toxins on a near-constant basis—everything from pesticides and chemicals in or on our foods, chemicals in our body products and home cleaning products, pollution in our air, and even off-gassing from furniture and carpets. Because of this daily exposure to toxins, our bodies are in a perpetual state of detoxification. The liver, gallbladder, kidneys, colon, skin, and lungs all work in concert to filter and remove these toxins on a daily basis.

But these detox organs and tissues can become overloaded, fatigued, or clogged, leaving you feeling like you don't have the energy to complete your daily run or fight off that cold. To help you learn how to properly cleanse your system, we did a deep dive into what makes detox cleanse products tick and rounded up our 6 favorite options. So if you’re interested in supporting the detox process and improving your well-being, keep reading.

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Disclaimer: Exercise caution when taking supplements. Always make sure to consult with your doctor before trying a new supplement or pill. Weight-loss supplements are not a substitute for a balanced diet and regular exercise. Any supplements taken should be used in accordance with a healthy lifestyle. Any weight loss of more than a pound per week over a long period of time is unusual and should be monitored by a doctor.

The Best Detox Cleanses - Our Top Picks

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Detox Pure

Detox Pure

SPECS

  • Form: Capsules
  • Active ingredients: Acai berry, spirulina, kelp, chlorella, alfalfa
  • Recommended doses: 2 capsules daily (ongoing)

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Detox Pure is designed as an ongoing (i.e., daily) maintenance product which is great because detoxing requires constant upkeep and is not as simple as a magic, 1-time use formula. It contains antioxidant-rich acai berry to support the detoxification process, plus superfoods like kelp, spirulina, and chlorella that supply important minerals, fatty acids, and natural fiber to support digestive and immune health. And because it comes in the form of small capsules, it’s easy and quick to take (unlike a detox smoothie or mixture you have to make every day).

What We Like

  • Daily formula for ongoing support
  • Algae superfoods for trace minerals, fatty acids, natural fiber, and detox benefits
  • Alfalfa to replenish supportive vitamins and minerals for the liver

What We Don't Like

  • A bit pricey for ongoing use
  • Limited ingredients

BUY: Detox Pure

RenewLife Cleanse Smart Advanced Total Body Program

RenewLife Cleanse Smart Advanced Total Body Program

SPECS

  • Form: Capsules
  • Active ingredients: Artichoke leaf extract, dandelion root extract, milk thistle seed extract, Cape Aloe leaf, LAG (larch arabinogalactan), and more.
  • Recommended doses: 1-2 Morning formula capsules + 1-2 Evening formula capsules

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RenewLife Advanced Total Body is a 30-day cleanse designed to promote regularity and work in harmony with your body's natural detoxification pathways to promote better well-being. The product contains two parts, a morning capsule, and an evening capsule, for around-the-clock support. The ingredient list contains herbs that support the liver and other detox organs, including milk thistle and chlorella. It also includes LAG (larch arabinogalactan), a prebiotic to support digestion.

What We Like

  • 30-day program for more complete detoxing
  • Clean ingredient list, free from any artificial additives or preservatives
  • Complete body detox support

What We Don't Like

  • Pills are larger and may be harder to swallow for some
  • 30-day program may be too long for some people to follow

BUY: RenewLife Cleanse Smart Advanced Total Body Program

Designs for Health PaleoCleanse Plus

Designs for Health PaleoCleanse Plus

SPECS

  • Form: Powder (add to water)
  • Active ingredients: Bone Broth protein, antioxidants, herbs (milk thistle & more), fiber, fruit, and vegetable blend
  • Recommended doses: 1 scoop (36g) mixed with 10oz water, daily

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This cleansing formula is unlike others on the market because it contains 18 grams of protein which comes from bone broth—bone broth also has a variety of health benefits thanks to its gut-healing potential. And the amino acids you get from the protein are essential to phase II detoxing; without them, released toxins can get "stuck" in the body. This formula also contains an array of nutrients, fiber, herbs, antioxidants, and more to support the complete detoxification process.

What We Like

  • Contains amino acids and sulfur to help toxins "escape"
  • Herbs to support liver cleansing
  • Supplies essential vitamins and minerals

What We Don't Like

  • Pricey
  • Taste isn’t for everyone

BUY: Designs for Health PaleoCleanse Plus

GNC Preventive Nutrition Complete Body Cleansing Program

Preventive Nutrition Body Cleansing Program

SPECS

  • Form: Liquid
  • Active ingredients: Antioxidant Blend, Fiber blend, Japanese Seaweed blend
  • Recommended doses: Drink 4 oz. of concentrate 4 times per day for 2 days

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GNC has created a robust formula with a proprietary antioxidant blend that combines nearly 40 ingredients, including aloe vera gel, milk thistle seed extract, and various plant foods rich with antioxidant and cleansing properties. They've also added a fiber blend to assist in digestive movement and various sea algae and plants, such as chlorella and wakame, to provide essential minerals to support the detox system.

The catch? There is no such thing as a one- or two-day complete cleanse. Toxins accumulate over the years and it takes time to remove them safely. However, if you follow a clean diet and lifestyle, "quick fix" products such as this may offer some benefits to help your system reboot.

What We Like

  • Antioxidant-rich; antioxidants are key during detox
  • Some natural fibers to support digestion
  • No artificial flavors

What We Don't Like

  • Contains sucralose
  • Contains preservatives such as potassium sorbate and sodium benzoate
  • Detoxing may take much longer than 2 days

BUY: GNC Preventive Nutrition Complete Body Cleansing Program

Metagenics AdvaClear - Daily Support for Detoxification

Metagenics AdvaClear - Daily Support for Detoxification

SPECS

  • Form: Capsule
  • Active ingredients: Artichoke leaf extract, watercress, Taurine, Sodium Sulfate, Pomegranate, Green Tea, milk thistle
  • Recommended doses: 2 capsules daily (ongoing)

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If you're looking to provide ongoing support to your body, Metagenics AdvaClear is a good option. It provides many essential vitamins and minerals, antioxidants, amino acids from taurine to support phase II detox, and herbs to support the liver, like milk thistle. And because this is a daily pill you take like any other vitamin, it's like constant background support for detoxification.

What We Like

  • Amino acids to support phase II detox
  • Green tea is decaffeinated
  • Milk thistle for liver support

What We Don't Like

  • Risk of overdosing on vitamins and minerals if you're also taking a multivitamin, so check the labels
  • Does not contain any fiber

BUY: Metagenics AdvaClear - Daily Support for Detoxification

What is a Detox Cleanse?

A detox cleanse is a method to assist the body's detoxification organs and tissues in removing toxins. By boosting liver function (our main detoxifier), improving digestion, and supplying key nutrients essential for the process, a good detox cleanse can help open the detoxification pathways, supporting the removal of toxins.

FAQs About Detox Cleanses


How long does it take to fully cleanse your body?

There is no magic number for a detox length. The amount of time it takes to detox depends on the number of toxins stored in your body and how well your body's detox pathways are functioning. Remember—there is no such thing as a one- or two-day complete cleanse. Toxins accumulate over the years so it takes time to remove them safely.

How often should you detox your body?

Detox frequency is individually-based on your diet and lifestyle. Rather than following strict guidelines, listen to your body and look for signals that it needs help, such as unnatural fatigue, frequent colds or illness, or new or worsening skin conditions.

The best way to reduce your need to cleanse is by avoiding as many toxins as possible through better food choices, body products, home cleaning products, and other sources of possible toxin exposure.

What foods should I avoid while detoxing?

It is imperative to eat clean while detoxing. Above all, that means no processed foods. Instead, choose whole foods and organic, wild or pasture-raised whenever possible. Be sure to include a full dose of healthy fats (think avocados, seeds, nuts, fatty fish like salmon, and olive oil) daily because fats are necessary in the detoxing process. It’s also important to try to maintain healthy eating post-detox if you want to maintain a toxin-free body.

Can I have coffee while detoxing?

Coffee is a diuretic, meaning it pulls water out of the body. Unfortunately, this is exactly the opposite of what you want during a cleanse. So skip that cup of morning joe and spring for herbal tea which supports your detoxing goals while also giving you a nice caffeine-like boost.

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

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