If you live 30 miles away from the office, a run commute might not be in the cards (unless you can take public transit part of the way!). However, if you live between 2 and 10 miles from work, a run commute is feasible, at least sometimes.
Think about how you'll travel to or from work—highways are fine for cars and buses, but they aren't safe routes for runners. Look online at maps, and scout out a well-lit route with minimal traffic ahead of time.